Posts Tagged ‘HIV/AIDS’

New HIV Test Approved by FDA

Posted in HIV testing on September 29th, 2009 by hiv_test – Comments Off

Each year over 50,000 people in the U.S. become infected with HIV. According to the Centers for Disease Control (CDC) more than 1.1 million Americans are living with HIV, and over one-quarter of them do not know it. HIV is most often transmitted through sexual intercourse or direct contact with infected blood, semen, or vaginal fluids, but it can also be transmitted through blood or organ donations. However, due to improvements in donor education and screening the risk of transmission through transfusions and transplants has decreased. These improvements now include the Abbott Prism HIV O Plus assay, an HIV antibody test.

The test, which was approved by the U.S. Food and Drug Administration in September 2009 is licensed for screening donated blood and blood specimens, and for screening specimens from organ donors. Prior to 1985, there were no tests available to screen for HIV in blood and organ donations, but nowadays donors and organs go through extensive testing. “The risk of acquiring HIV from a blood transfusion… is estimated to be 1 in 4 for every 600,000 transfusions. The risk… from organ transplantation is probably similar.”

The two most common blood tests used to previously detect HIV were the enzyme-linked immunosorbent assay (ELISA), and the Western blot assay, which are both antibody tests. These tests can only tell if a person has been infected with HIV, not how long they’ve been infected or if they have AIDS (acquired immune deficiency syndrome, the final stage of HIV disease).

This new HIV test will help decrease the number of HIV transmissions through blood transfusions and organ donations, and  help make the world a safer place.

*For the complete article, please refer to http://hivtestingblog.com/original-articles/

Share

Pact inked with Clinton Foundation

Posted in HIV DNA by PCR on September 11th, 2009 by hiv_test – Comments Off

Minister of Health, Dr. Leslie Ramsammy signed an agreement with the Clinton Foundation HIV/AIDS Initiative (CHAI) that supports a program in various areas. The program includes a steady supply of aniretroviral medication, CD4 testing, diagnosis and monitoring and nutritional supplements among other initiatives.

Alfredo Idiarte of CHAI said his organization is committed to the program and will work towards making it more comprehensive. He also said that CHAI is looking at providing deoxyribonucleic acid Polymerase chain reaction (DNA PCR) tests for infant diagnosis. The DNA PCR test looks for direct (DNA) evidence of the virus rather than the antibodies. Currently the tests do not detect evidence of the virus in children younger than 18 months. Early detection could drastically improve treatment options.

*For the original article please refer to http://hivtestingblog.com/original-articles/.

Share

HIV Testing and Diagnosis in Infants and Children

Posted in HIV testing on August 7th, 2009 by hiv_test – Be the first to comment

MAJOR RECOMMENDATIONS


Responsibilities of Child Healthcare Providers

As part of the initial newborn evaluation, the pediatric clinician should determine whether human immunodeficiency virus (HIV) testing of the mother has been completed properly and should follow up on any outstanding laboratory values.

Pediatric clinicians should obtain testing for HIV beyond the neonatal period if the child presents with signs and symptoms of HIV disease. Testing should be performed in children who have not yet been tested when risk factors for HIV infection exist in the child or one of his/her parents.

Laboratory Tests for HIV in Newborns, Children, and Adolescents

Because positive antibody results alone do not establish infection in children younger than 18 months of age, assays to detect virus (HIV deoxyribonucleic acid [DNA] polymerase chain reaction [PCR] or viral culture) should be used for diagnosis (see Figure 1 in the original guideline document).

In children older than 18 months of age, HIV infection may be diagnosed on the basis of a positive HIV antibody test (enzyme-linked immunosorbent assay [ELISA]) and a confirmatory test, such as Western blot.

Because of the time period between infection and the development of detectable antibodies, children/adolescents exposed via sexual activity, sexual abuse/assault, or infected blood who have an initial negative test result should be retested at 1 month, 3 months, and 6 months after exposure.

Because a child with end-stage HIV disease may become HIV-antibody seronegative as a result of severe humoral immunodeficiency, children who are clinically suspected to be HIV-infected yet test HIV antibody negative should be tested by DNA PCR (or HIV culture).

Children older than 18 months of age with an indeterminate Western blot result should be retested as soon as possible. If the Western blot result remains indeterminate, the patient should be tested for HIV-2 or specific viral tests (e.g., DNA PCR) for HIV-1 should be performed.

Rapid testing and expedited preliminary test results prior to Western blot confirmation should generally be used only when immediate information is needed to determine the need for post-exposure prophylaxis in the labor/delivery, newborn, or other acute exposure settings, or when the person who is being tested is unlikely to return for a follow-up visit.

When preliminary diagnostic tests are used for expedited HIV testing, a preliminary positive test result must be confirmed with a Western blot as soon as possible.

Testing for HIV Antibody

See the original guideline document for discussions of screening tests, confirmatory testing of positive results, and rapid test assays.

Testing for HIV or Viral Components

Clinicians should test children younger than 18 months of age who are born to an HIV-infected mother for HIV using one of the following methods:

* HIV DNA PCR (preferred method)

* HIV culture (acceptable method)

Because infection can only be confirmed with two positive test results performed on samples collected at different times, a repeat sample should be obtained promptly for any child with a single positive test result.

In an infant younger than 18 months of age, HIV can be reasonably excluded with two negative HIV viral tests, one at 1 month of age or older, and the other at age 4 months or older.

Ideally, a DNA PCR should be obtained for HIV-exposed infants at each of the following time points:

* at birth

* at 2 weeks of age

* at 4 to 6 weeks of age

* at 6 to 12 weeks of age

* at 4 to 6 months of age

See the original guideline for discussions of HIV DNA PCR, HIV culture, plasma HIV RNA, and HIV antigen detection.

HIV Counseling and Testing

In New York State, written informed consent from the child’s biological parent or legal guardian must be obtained before HIV testing can be performed in children except in certain specific circumstances, such as expedited testing, newborn screening, and follow-up PCR testing, and when testing is urgently necessary to provide medical care for a life-threatening condition.

When HIV testing of a child is performed, the parents should be considered for testing as well.

If a child is found to be perinatally HIV infected, his/her siblings also should be tested.

If HIV infection is newly diagnosed in a woman, all of her children should be strongly considered for testing, even if they are asymptomatic.

Pre-Test Counseling

The clinician should counsel the child’s parent or guardian or the child/adolescent with capacity to consent prior to HIV testing (see Table 2 in the original guideline document).

In New York State, a minor’s right to consent for or refuse HIV testing is based on his/her capacity to understand, without regard to chronological age, what an HIV antibody test actually tests for, the implications/consequences of being HIV infected, and why he/she is at risk for HIV.

The clinician should arrange for follow-up visits at the time of testing and should note in the patient’s medical record that counseling was provided and written consent was obtained when required.

When rapid testing is obtained and will yield a preliminary result during the visit, the clinician should first ensure that the patient/parent is emotionally able to receive a positive result and that mental health services are available for patients receiving a positive result.

Obtaining Consent

See the original guideline document for a discussion New York State laws on obtaining consent for HIV testing in children and adolescents for HIV testing.

Post-test Counseling

Counseling after a Patient Receives a Positive Test Result

Positive HIV test results should be presented in person to the appropriate individual (patient, parent, or guardian). A clinician should not communicate results to a patient or family member by telephone or mail.

Clinicians must respect an adolescent’s right to confidentiality concerning HIV status.

The clinician should explain the test results and should provide general information about available treatment.

The clinician should discuss the implications of the HIV Reporting/Partner Notification law (refer to the section “HIV Reporting and Partner Notification” below).

The clinician should provide or arrange for necessary referrals for treatment and supportive services.

The clinician should discuss methods of risk reduction and advise the family to inform medical personnel of the child’s HIV status during any medical care visit.

Counseling After the Patient Receives a Negative Test Result

When telling a patient that his/her test result is negative, the clinician should educate the patient on how to reduce the risk of transmission in the future.

HIV Reporting and Partner Notification

Since June 2000, New York State has required HIV reporting and partner notification for all confirmed positive HIV tests (unless testing occurred at an anonymous site) and HIV-related tests.

During pre-test counseling, parents/children should be informed that if their HIV test result is positive, their names will be reported to the New York State Department of Health.

Parents/children should be informed during pre-test counseling that if they provide the names of sexual or needle-sharing partners, the provider is required to report these names to the State Health Department. They should also be informed that if the test results are positive, their partners will be notified that they have been exposed to HIV.

All sexually active HIV-infected adolescents should be informed about the importance and benefits of notifying partners of their possible exposure to HIV.

Adolescents who are undergoing HIV testing should be questioned regarding the potential for domestic violence if their partners were notified. If domestic violence is a concern, partner notification should be deferred until the risk of harm to the patient (or one close to the patient, e.g., child) is eliminated.

HIV Testing of Older Children and Adolescents With the Capacity to Consent

Clinicians should be knowledgeable about New York State laws pertaining to adolescent consent and confidentiality and should educate their patients about these laws (see the National Guideline Clearinghouse (NGC) summary of the New State Department of Health guideline Identification and Ambulatory Care of HIV-exposed and -infected Adolescents).

In New York State, older children and adolescents who are judged capable of understanding the informed consent process may give written informed consent for HIV testing.

Parents cannot be informed of their child’s HIV test results without the explicit consent of the child or adolescent who is deemed capable of providing consent.

Ideally, HIV testing of older children and adolescents should occur in a comprehensive care setting that provides social support, ancillary services, and ongoing health care.

HIV Testing in Children in Foster Care

Within 5 days of entering the foster care system, all children must be assessed for capacity to consent for HIV testing. If a child is determined not to have capacity to consent, an HIV risk assessment must also be completed within the first 5 days of entering foster care. Children already in foster care must be assessed for HIV risk factors at least 60 days prior to their next scheduled periodic medical examination. If it is determined that a child may have the capacity to consent, an assessment of capacity to consent must be made and documented by authorized foster care agency staff within 30 days of the child’s entry into foster care. An HIV risk assessment must also be completed within this timeframe.

If one or more risk factors are present, a child in foster care should be offered HIV testing, or if the child lacks capacity to consent, he/she should be tested for HIV infection.

Adolescents and older children in foster care with the capacity to consent for HIV testing have the right to either consent for their own test or refuse testing.

For the commplete article, please refer to http://www.guidelines.gov/summary/summary.aspx?doc_id=6834

Share

How Is HIV Different in African Americans?

Posted in HIV in African Americans on August 7th, 2009 by hiv_test – Be the first to comment
It is a common fact that HIV does not discriminate against who it infects; however, having HIV doesn’t always mean the same thing…especially if you’re African American. Research has shown that African Americans have higher rates of HIV infections, they get sicker faster, and get treatment later than other ethnicities. There are many myths that exist in the community to explain why more African Americans die from HIV that other races. There is a cure for HIV, but they won’t give it to black people, or there is a vaccine, but the government doesn’t want black people to know about it. The truth is that there are factors, other than HIV itself, that cause the virus to acct more aggressively in African Americans. On average, African Americans tend to wait longer to get tested which causes their response to HAART (highly active antiretroviral treatment) to be less effective, the side effects to treatment medications are often worse than in other patients, and other lifetstyle and environmental factors that are prevalent in African Americans have been shown effect HIV and HIV treatment.
A group of HIV specialists and researchers were brought together to explain these findings, and the answers are both shocking ans surprising. African Americans are predisposed to some factors that affect HIV infection, and there are also several lifestyle and living factors that contribute to the effects as well.
Although we still have a lot to learn about HIV and why it affects certain groups of people differently than others, we are making lots of progress in research. While there are many myths and explanations for why HIV is worse in African Americans, most of them are false. The real reasons for this phenomenon lie within several factors that surround the HIV-positive person, including diet, living conditions, adherence, and more. Perhaps with these findings we will be able to develop a more effective and suitable HIV treatment plan for everyone.
*For the complete article, please visit http://hivtestingblog.com/original-articles/
Share

Researchers identify new strain of HIV derived from gorillas

Posted in Uncategorized on August 4th, 2009 by hiv_test – Be the first to comment

A new virus is difficult to detect by tests because it is not closely related to the other three HIV variants.

French researchers have identified a new human immunodeficiency virus, the first derived from gorillas, a report said Monday.

A new virus is difficult to detect by tests because it is not closely related to the other three HIV variants.

The three previous HIV variants came from chimpanzees. The new findings indicate that gorillas, in addition to chimpanzees, are likely sources of HIV, the researchers concluded in a report published in the weekly Nature Medicine journal.

The new virus, called RBF 168, was detected in a 62-year-old woman who moved to Paris, France, from the western Africa nation of Cameroon, the report says. She tested positive for HIV in 2004, and researchers led by Jean-Christophe Plantier identified the virus as being closely related to a recently discovered simian immunodeficiency virus (SIV).

The new gorilla virus “has many of the biological properties necessary for human infection,” the report says.

“The human case described here does not seem to be an isolated incident, as before coming to Paris the subject had lived in the semiurban area of Yaounde, the capital of Cameroon, and reported no contact with apes or bush meat,” the researchers said.

That would indicate that the woman contracted the virus from another human.

The significance of the latest findings is difficult to determine without more information, said Robert C. Gallo, who co-discovered HIV in 1984.

“It’s yet to be known,” Gallo said. “It could be zero. … Let’s see a more full report on this individual and let’s see wider testing.”

Even if the new variant proves lethal, it’s not likely to increase AIDS infections, said Gallo, director of the Institute of Human Virology at the University of Maryland School of Medicine. There are so many HIV variations, he said, that one more is not likely to make a difference.

The new virus is difficult to detect by conventional tests because it is not closely related to the other three HIV variants.

“This demonstrates that HIV evolution is an ongoing process,” co-researcher David Robertson of the University of Manchester said in a release. “The virus can jump from species to species, from primate to primate, and that includes us; pathogens have been with us for millions of years and routinely switch host species.”

HIV can lead to acquired immunodeficiency syndrome, which attacks the body’s immune system, giving rise to lethal infections. Patients diagnosed with HIV can take medications to delay or stop HIV from developing into AIDS. There are 33 million confirmed cases of AIDS worldwide.

The unnamed woman has no signs of AIDS and remains untreated, Nature Medicine said.

The most likely explanation for the emergence of the new virus is gorilla-to-human transmission, though researchers say they cannot rule out the possibility that the chimpanzee SIV gave rise to the new strain “either indirectly by transmission to gorillas and then to humans or directly by transmission to humans and also to gorillas.”

Researchers said they don’t know how widespread the virus is among humans.

“The human prevalence of this new lineage remains to be determined,” the report says, adding that “it could be circulating unnoticed in Cameroon or elsewhere.”

Western Central Africa bears close watching, the researchers suggest.

“In conclusion, our findings indicate that gorillas, in addition to chimpanzees, are likely sources of HIV-1,” the report states. “The discovery of this novel HIV-1 lineage highlights the continuing need to watch closely for the emergence of new HIV variants, particularly in western central Africa, the origin of all existing HIV-1 groups.”

Co-researcher Robertson noted that the new virus may not be restricted to Africa.

“It also highlights how human mobility can rapidly transfer a virus from one geographical location to another as has been dramatically evident with the recent emergence of swine flu,” he said.

For the complete article, please refer to www.cnn.com

Share

Call for Cheap Access to Female Condoms

Posted in HIV and AIDS - World Health on July 24th, 2009 by hiv_test – Be the first to comment

Female condoms have played a large role in women protecting themselves against HIV for many years, and at the 12th National AIDS Conference the new FC2 Female Condom was promoted as a key role in Thailand’s HIV prevention strategy.

The FC Female Condom has been on the market since 1988; however, users have voiced their complaints about the product including it’s difficulty to use, noise, and it being uncomfortable. In response to these complaints manufacturers developed the FC2 Female Condom, which is made of nitrile rubber creating a more comfortable use.

Thailand has had a longstanding battle with HIV, and although they studied the use of female condoms for use in their HIV/AIDS plan in 1990 the studies were halted last year with no results. Production of female condoms has increased by as much as 14 million in the past four years and are currently distributed in 90 million countries, but due to importation costs the FC2 has not been made accessible in Thailand.

According to Tisssadee Sawangying, a health coordinator who took part in the National AIDS Conference, “the government should work hard to increase alternative options for women to protect themselves from HIV/AIDS infection.” Having an option such as the FC2 available for women in Thailand and all over the world would greatly increase their options when it comes to protecting themselves.

*For the complete article, please visit http://hivtestingblog.com/original-articles

Share

Health District Cuts $400,000 Grant that Helped HIV Sufferers Stay on Medications, Navigate Insurance System

Posted in HIV infection, Living with HIV on July 13th, 2009 by hiv_test – Be the first to comment

On Wednesday, the Palm Beach County Health Care District board unanimously approved a planned $400,000 cut to the Comprehensive AIDS Program’s case management services despite testimony from 10 patients and providers that the services are vital.

Case management helps patients to stay on complex drug regimens, navigate insurance plans, and keep important appointments, advocates told the board. “If a person stops taking their medication, not only does their own health suffer, they become more infectious to other people,” said Yolette Bonnet, CEO of the AIDS program.

Anita Byrd of West Palm Beach said: “I was addicted to street drugs, and I have been clean now for 11 years because of case management. They found me in places where people never want to come.”

The HIV/AIDS grant was among a raft of cuts the board made in its tentative 2010 spending plan. Out of a $250 million budget, the special taxing district must slash $31 million due to increased demands on its insurance programs, which will serve nearly 40,000 people this year. School nurses’ hours were cut from 40 hours a week to 33 to save $3 million.

Jonathan Satter, the board’s chair, said he felt “darned if he did, darned if he didn’t” cut services or raise taxes to preserve them. “We cannot be the sole source for every program,” he said, noting he hoped the AIDS program was seeking foundation money.

For the complete article, and for more information from the Centers for Disease Control and Prevention, please refer to http://www.cdcnpin.org/

Share

FDA Approves Expanded Use Of HIV Drug

Posted in HIV treatment, HIV-AIDS Treatment on July 13th, 2009 by hiv_test – Be the first to comment

Merck announced on Thursday that the FDA has approved expanded use of its HIV drug, Isentress, Reuters. Isentress has been FDA-approved since 2007, but was limited “to use in patients who had drug-resistant strains or were failing on other therapies, also in combination with other HIV drugs. Now it can be used in all adult patients,” the AP/CNBC.com reports. According to AP/CNBC.com, “Isentress is an integrase inhibitor, meaning it works by blocking the enzyme integrase, one of three types of enzymes the AIDS virus uses to reproduce and infect cells”

For the full article, please refer to http://www.medicalnewstoday.com/articles/157219.php

Share

Ten Ways to Take Care of Yourself When You Have HIV Disease

Posted in HIV infection, Living with HIV on July 10th, 2009 by hiv_test – Be the first to comment

1) Take Responsibility For Your Health and Your Life.
2) Get A Support Network To Be With You In Good and Bad Times.
3) Find A Health Provider With Whom You Can Build A Relationship.

Some resources for HIV treatment information include:
www.aidsinfo.org 1-949-248-5843
www.aidsmeds.com
www.catie.ca 1-800-263-1638 (toll-free in Canada)
www.gmhc.org 1-800-AIDS-NYC
www.projectinform.org 1-800-822-7422
www.natap.org 1-888-26-NATAP
www.thebody.com
www.tpan.com 1-773-989-9400

4) Take HIV Medications When You Need Them.
5) Maintain Good Nutrition.
6) Get Up and Do Some Exercise.
7) Learn About Benefits and Services You Might Be Eligible For.

There are many benefits and services available to people living with HIV disease but you have to know about them and their requirements in order to get them. Benefits you might be eligible for include:

  • SSDI (Social Security Disability Insurance) this is the program you paid into when you worked
  • SSI (Supplemental Security Income Program) this is the disability program for folks who didn’t have enough points for SSI or who have never worked
  • ADAP and ADAP Plus — state-run HIV drug assistance program
  • Medicaid — medical program associated with Welfare or SSI
  • Medicare — medical program associated with SSDI
  • Short-term Disability
  • Long-term Disability
  • HASA (HIV/AIDS Services Administration)
  • Section 8 and other housing programs
  • Food services
  • Legal services
  • Case management services
  • Home health services
  • Welfare

8 ) Get A Life Outside HIV.
9) Stop Stressing…So Much.
10) Ask For Help When You Need It .

Share

Global Fund Increases AIDS, Tuberculosis And Malaria Prevention And Treatment Measures By 30-50% Over One YearGlobal Fund Increases AIDS, Tuberculosis

Posted in HIV and AIDS - World Health on July 9th, 2009 by hiv_test – Be the first to comment

Today the Global Fund to Fight AIDS, Tuberculosis and Malaria announced its latest prevention and treatment numbers, noting in particular that Global Fund-financed programs have put 2.3 million people on treatment for HIV/AIDS, 5.4 million people have been treated for tuberculosis, and 88 million insecticide-treated nets have been distributed to prevent malaria infection. In addition, more than 500,000 HIV-positive pregnant women have been treated to prevent their babies from being born with HIV.

These latest results strengthen evidence that investments during the past five years have resulted in the most significant progress ever achieved in the global fight against these three diseases. Recent evidence suggests that global mortality from tuberculosis is now declining, AIDS mortality among adults in several high-burden countries in Africa is declining, and malaria elimination efforts have made tremendous progress, with reductions in the number of cases and malaria-related child mortality falling between 50% and 80% in a growing number of countries.

Together, AIDS, tuberculosis and malaria kill about six million people per year. With grants worth $16 billion in 140 countries around the world, the Global Fund has become the world’s leading global public health financier.

For the full article, please refer to http://www.medicalnewstoday.com/articles/156875.php

Share

WHO warns of risks of TB vaccine to HIV-infected infants

Posted in HIV and AIDS - World Health on July 3rd, 2009 by hiv_test – Be the first to comment

The World Health Organization (WHO) has warned that the tuberculosis (TB) vaccine is of great risks to HIV-infected infants, Tanzanian local daily the Guardian reported on Thursday.

Through its research published in the International Public Health journal, the WHO noted that HIV-infected infants risked contracting a deadly form of tuberculosis from the Bacille Calmette-Guerin (BCG) vaccine instead of receiving protection against the disease, the report quoted a WHO statement issued on Wednesday in Dar es Salaam as saying.

For the complete article, please refer to http://news.xinhuanet.com/english/2009-07/02/content_11641405.htm.

Share

Obama urges HIV testing

Posted in HIV testing on July 1st, 2009 by hiv_test – 2 Comments

On the fourteenth National HIV Testing Day President Obama issued a statement supporting annual testing and safe-sex practices.

Obama informed everyone that one in five Americans living with HIV do not know they are infected, and that those people are the ones who transmit HIV the most. However, Obama also noted that once people become aware of their status they take the steps to reduce transmitting HIV to their partners.

While Obama admitted that direct impacts of HIV are not widespread, seeing as how higher rates exist within gay/bisexual men, African Americans, and Latinos – he acknowledged that if a citizen is infected with HIV every nine-and-a-half minutes it affects all Americans.

Using these statistics Obama pledged to implement a comprehensive National HIV/AIDS Strategy (NHAS) to provide better care for those already living with HIV and prevent future transmission in others. However, the government cannot be held responsible for all these practices. Obama urged all Americans to practice safe-sex, regularly get tested, and help eliminate the stigma attached to living with HIV. If the government and the people work together we can decrease the rates of HIV and increase our care towards one another.

*For the complete article, please visit http://hivtestingblog.com/orignal-articles/

Share

Black Gay Men May Be At Increased HIV Risk

Posted in HIV infection on July 1st, 2009 by hiv_test – Be the first to comment

In a study looking at social and sexual mixing between ethnic groups in men who have sex with men, researchers show that social barriers faced by black gay men may have a serious impact on their health and well-being.

In the US, there is a disproportionate burden of HIV infection in Black Americans, who accounted for nearly half of all HIV/AIDS cases diagnosed in 2006 – four times the national average.

A total of 1,142 gay men took part in computer-assisted interviews. They were asked about their own ethnicity, the race of their sexual partners in the last six months, their perception of how easy it is to meet sexual partners of different ethnicities, where they meet sexual partners, their view of HIV infection risk and the predominant race of their network of friends.

Black gay men are the least preferred of sexual partners by other races. Black men are perceived to be riskier to have sex with, which can lead to men of other races avoiding Black men as sexual partners. They are also perceived as less welcome in the common social venues of gay men in San Francisco. As a result, Black men are three times more likely to have sexual partners that are also Black, than would be expected by chance alone.

The authors conclude: “The racial disparity in HIV observed for more than a decade will not disappear until the challenges posed by a legacy of racism towards Blacks in the US are addressed.”

For the complete article, please refer to http://www.sciencedaily.com/releases/2009/06/090629114536.htm

Share

HIV testing technology in US needs to change or risk missing acute infections

Posted in HIV testing on June 29th, 2009 by hiv_test – Be the first to comment

A fourth generation HIV testing assay detected almost two-thirds of individuals with acute HIV infection, investigators report in an article published in the online edition of the Journal of Acquired Immune Deficiency Syndromes. The researchers believe that their results show the ARCHITECT HIV Ag/AB Combo Assay to have significant advantages, including the time needed to obtain a result compared to the current pooled HIV RNA testing strategy used to diagnose acute HIV infection. Such assays are already routinely used in the United Kingdom.

Diagnosis of acute HIV infection relies on detection of HIV virus using viral load tests, or p24 antigen. Pooled HIV viral load testing has been shown to be an effective means of diagnosing acute infections. However, it is slow, it typically taking between seven and 21 days to obtain the results, cumbersome, and labourious. It is therefore not a realistic technology for resource-limited settings, nor for addressing the problem of ongoing transmission from people during acute infection.
The ARCHITECT Combo assay was positive for 13 of the 21 acute samples. The median viral load of individuals testing positive with this technology was significantly higher than that of individuals testing negative (662,ooo copies/ml vs. 3576 copies/ml).

“The failure to diagnose acute HIV infection represents an important public health problem”, note the investigators, “persons with primary infection may be up to 10 times more likely to transmit HIV per sexual act than are individuals with established infections”.

For the complete article, please refer to http://www.aidsmap.com/en/news/D9111996-68D9-4F3D-A499-C9559819B045.asp.

Share

A generation born with HIV/AIDS defies the odds

Posted in HIV infection, hiv transmission on June 25th, 2009 by hiv_test – 3 Comments

Babies who were born with HIV/AIDS in the 1980s have defied initial expectations. No one expected them to live long.

Since the mid-1990s in developed countries, antiretroviral drugs have largely prevented mothers from transmitting HIV/AIDS to their babies.

Nearly 30 young adults and teenagers who were born with HIV/AIDS meet every week at the Jackson Memorial Hospital in Miami, Florida. “We don’t want to talk about HIV every day,” said Eric Koumbou, 19. “If you talk about HIV and you don’t have it and I do, sometimes it makes me angry or makes me sad.”

For the complete article, please see http://www.cnn.com/2009/HEALTH/06/22/hiv.children.generation/index.html?eref=ib_topstories.

Share

To Fight AIDS, State Recommends Routine HIV Screening

Posted in HIV and AIDS - World Health on June 25th, 2009 by hiv_test – Be the first to comment

BOSTON — In an effort to reduce AIDS rates in Massachusetts, state public health officials recommended that everyone 13 and older get HIV-tested as part of their routine medical care.

The goal is to make HIV screening as common as cholesterol tests and blood pressure monitoring. That way, HIV infections could be treated immediately, before they progress to full-blown AIDS.

Currently, about a third of people in Massachusetts with HIV develop AIDS within two months of diagnosis. Lauren Smith, medical director at the state Department of Public Health, says that number is too high.

“That tells us that, in fact, they were infected with HIV probably for many years — possibly a decade,” says Smith, “and suggests that we lost many opportunities to intervene and provide them very effective care that can ensure that they live longer and healthier.”

Smith also says the state’s health care system could save money if HIV is detected and treated earlier. HIV testing remains voluntary in the state and is free at many doctors’ offices and health clinics.

“It would be rolled into routine clinical care,” says Smith. “That’s why we screen for cholesterol, that’s why we take people’s blood pressure — it’s because we can do something very effective about it. Similarly, we need to screen everyone for HIV because we have effective treatments that can make a big difference in this condition.”

For the complete article, please refer to http://www.wbur.org/2009/06/25/hiv-testing.

Share

Discrimination in Visa Laws Poses Risk to Those With AIDS, Rights Group Says

Posted in HIV and AIDS - World Health on June 24th, 2009 by hiv_test – Be the first to comment

International migrant workers, foreign students and political refugees are often endangered by laws that discriminate against people with AIDS, the advocacy group Human Rights Watch reported last week.
The report describes how guest workers from poor countries like the Philippines and Sri Lanka working in wealthy ones like Saudi Arabia may be given mandatory H.I.V. testing — sometimes without their knowledge — and deported, often without being able to claim back wages and sometimes after imprisonment without treatment.
For the complete article, please see http://www.nytimes.com/2009/06/23/health/23glob.html?_r=1.

Share

Approach For Possibly Eradicating HIV Infection Discovered

Posted in HIV-AIDS Treatment on June 24th, 2009 by hiv_test – Be the first to comment

With the new data, scientists may have new leads for innovative treatments for AIDS-HIV.

The American and Canadian researchers with Oregon State University’s Vaccine and Gene Therapy Institute (VGTI) of Florida and the University of Montreal, have found what they believe is a more effective treatment and potentially even cure for AIDS-HIV, based on the discovery of the virus’ hiding places.

According to study co-leader Dr. Rafick-Pierre Sekaly, “You have to target not the virus, but the cells in which the virus is hiding. And that I think it is a very different concept than what everybody has been pushing for. That clearly is a major finding that we have got to the table.” He added, “This would make it possible to destroy cells containing a virus while giving the immune system time to regenerate with healthy cells.”

Dr. Sekaly says, he is “very optimistic” that researchers will be able to develop new drugs to target the hiding spots identified with their new research.

For the complete article, please refer to http://www.healthnews.com/medical-updates/no-more-hiding-virus-causing-aids-hiv-3343.html.

For the press release, please refer to http://www.sciencedaily.com/releases/2009/06/090621143312.htm.

Share

Porn industry clinic takes anti-HIV steps

Posted in adult film industry on June 16th, 2009 by hiv_test – Be the first to comment

The Adult Industry Medical Healthcare Foundation, reacting to a case disclosed last week, says it’s increasing database controls and urging producers to not accept paper test results from performers.

In an effort to prevent the possible spread of HIV in the adult film industry, the San Fernando Valley-based health clinic that serves the porn industry said Monday it is stepping up controls in its online database and urging producers not to accept paper copies of test results.

For the complete article, please refer to http://www.latimes.com/features/health/la-me-porn-hiv16-2009jun16,0,2659497.story.

Share

Mothers Helping Mothers Stop HIV

Posted in HIV and AIDS in Africa on June 12th, 2009 by hiv_test – Be the first to comment

Mothers2Mothers program aims to prevent AIDS virus transmission to infants.

At the World Economic Forum on Africa, the impact of HIV/AIDS on African countries is being addressed. The forum has honored one program that helps prevent mother-to-child transmission and turns stigmatized women into role models.

By giving the Mothers2Mothers program the Schwab Award, Falk says the World Economic Forum recognizes its success as a socially conscious business – combining the best of the private and public sectors.

For the complete article, see http://www.voanews.com/english/Africa/2009-06-11-voa18.cfm.

Share